Canned Heat were one of the first blues bands I heard, and On the Road Again is one of my favourite tracks. The band's harp player Alan Wilson (a.k.a. the Blind Owl) does something amazing in this song, using a uniquely tuned harp to get an impossible (without overblows) note during the solo.

I am following the single version of this song, rather than the extended album version, as I think the more concise intro and outro are, frankly, better!
 
In this lesson:
 
27 minute video lesson to download and keep forever
Step by step method on every note
Subtleties, licks and tricks
Full printable tab sheet
 
KEY: A diatonic harmonica